FACTORS ASSOCIATED WITH ADHERENCE TO TYROSINE KINASE INHIBITOR THERAPY IN CHRONIC MYELOID LEUKEMIA
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Abstract
Objective: Determine factors affecting treatment adherence of patients with chronic myeloid leukemia who are being treated with tyrosine kinase inhibitors at Bach Mai Hospital. Participants and Methods: Cross-sectional study on 144 patients with chronic myeloid leukemia treated at Bach Mai Hospital from April 2023 to April 2024. Results: Mean age was 57.46 ± 13.6 years, with the 35-60 age group comprising 57.6%. 42.1% had unstable employment. 40% had income < 5 million VND/month, and 40.3% had 5-10 million VND/month. Medication adherence > 80% was achieved by 76.4%, and overall treatment adherence was 75%. Education level and income significantly affected patient adherence to medication and treatment. Conclusion: Adherence to TKI treatment is crucial for CML patient outcomes. Education level and income significantly affect treatment adherence.
Keywords
Chronic myelogenous leukemia (CML), Tyrosine kinase inhibitor (TKI), adherence
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References
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