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Date Published: 19/12/2024
Abstract Views: 33
Views PDF: 4
DOI: 10.52322/jocmbmh.143.0205
Issue
Vol. 2 No. 143 (2024)
Section
Case reports/Case series
How to Cite
Nguyen Tuan, T., Do Thi Vinh, A., Le Lan, A., Pham Thi Thu, H., Ton Ai, T., & Ton Ai, T. (2024). ANALYSIS OF CELLULAR IMMUNE MARKERS IN CEREBROSPINAL FLUID OF LYMPHOMA PATIENTS AT THE HEMATOLOGY CENTER - BACH MAI HOSPITAL. Journal of Clinical Medicine Bach Mai Hospital, 2(143), 36-42. https://doi.org/10.52322/jocmbmh.143.0205

ANALYSIS OF CELLULAR IMMUNE MARKERS IN CEREBROSPINAL FLUID OF LYMPHOMA PATIENTS AT THE HEMATOLOGY CENTER - BACH MAI HOSPITAL

Tung Nguyen Tuan1, , An Do Thi Vinh1, Anh Le Lan1, Hang Pham Thi Thu1, Thuc Ton Ai1, Thuc Ton Ai1
1 Trung tâm Huyết học và Truyền máu, Bệnh viện Bạch Mai

Author contact

  • Contact information: Tung Nguyen Tuan
  • Email: tunghhbm@gmail.com
  • Address: Trung tâm Huyết học và Truyền máu, Bệnh viện Bạch Mai

Main Article Content

Abstract

Objectives: Determination of the diagnostic value of central nervous system invasive lymphoma by flow cytometry compared with cytogenetic methods. Participants and Methods: Cross-sectional description of 33 patients with lymphoma or 6 suspected lymphoma patients with neurological manifestations who underwent cerebrospinal fluid flow cytometry at Bach Mai Hospital from January 2022 to December 2023. Results: Abnormal lymphoid markers of lymphoma were detected in 23/33 cerebrospinal fluid samples by flow cytometry and 10 samples by morphological examination. Of the 6 patients with suspected lymphoma, 3 were newly diagnosed by immunomarker analysis, which significantly increased the detection rate compared to morphological testing in cerebrospinal fluid samples alone. Conclusion: This study showed that morphological testing combined with flow cytometry significantly increased the detection rate compared to morphology alone in cerebrospinal fluid samples.

Keywords

cerebrospinal fluid, immunomarkers, lymphoma

Article Details

References

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